Description
Product Characteristics: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of UPP1 in mouse tissue homogenates, cell lysates.
Target Information: The 2 known types of pyrimidine nucleoside phosphorylases, uridine phosphorylase (UP\, EC 2.4.2.3) and thymidine phosphorylase (TP\, EC 2.4.2.4), in the presence of orthophosphate, catalyze the reversible phosphorolysis of uridine and thymidine or deoxyuridine, respectively, to free bases and ribose-1-phosphate or deoxyribose-1-phosphate. Pyrimidine nucleoside phosphorylases can add ribose or deoxyribose to pyrimidine bases to form nucleosides that can be incorporated into RNA or DNA (Watanabe and Uchida, 1995 [PubMed 7488099]).[supplied by OMIM, Aug 2009]